CSP: Making sense of inflammatory markers
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Common Sense Pathology is a regular, case-based series on practical pathology for GPs. It is a joint initiative of the Royal College of Pathologists of Australasia and Australian Doctor.
The acute-phase reactants most commonly used for diagnostic purposes are CRP and ESR. Although these two markers lack the specificity to distinguish among the many possible causes of inflammation, they are a simple, cost-effective and valuable diagnostic tool to distinguish inflammatory from non-inflammatory conditions, and to monitor the response to treatment for a number of disorders.
The authors are Associate Professor Stephen Adelstein and Dr Alan Baker.
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